This infographic illustrates the significant contributions of U.S. global health investments, showcasing their role in reducing disease burdens, expanding access to treatment, and strengthening national health systems. It provides data-driven insights into the success of these programs in fighting HIV, malaria, tuberculosis, and neglected tropical diseases, as well as improving global health security against emerging threats like COVID-19 and Ebola. Key statistics demonstrate how investments in health infrastructure, surveillance, and workforce training have saved millions of lives and prevented widespread outbreaks. The infographic underscores the urgent need to maintain and expand these efforts, cautioning that program cuts would not only weaken health systems but also increase global risks, making future crises more difficult and expensive to manage.